Arboreto is a tool to infer gene regulatory networks in RNA-seq data. The Arboreto framework uses GRNBoost2 and an improved GENIE3 version. GRNBoost2 uses a gradient boosting approach for gene network inference.
RNA-seq; Molecular genetics; Gene regulation; Transcriptomics
Moerman T, Aibar Santos S, Bravo Gonzalez-Blas C, Simm J, Moreau Y, Aerts J, Aerts S "GRNBoost2 and Arboreto: efficient and scalable inference of gene regulatory networks." Bioinformatics. 2019 Jun 1;35(12):2159-2161. https://doi.org/10.1093/bioinformatics/bty916
PMID: 30445495
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