BRIE (Bayesian regression for isoform estimation) is a tool to quantify splicing from RNA-seq data. The BRIE algorithm learns prior distribution isoform proportions from the sequences in samples using a Bayesian hierarchical model.
Genetic variation; RNA-seq; RNA splicing
Huang Y, Sanguinetti G "BRIE: transcriptome-wide splicing quantification in single cells." Genome Biol. 2017 Jun 27;18(1):123. https://doi.org/10.1186/s13059-017-1248-5
PMID: 28655331
PMCID: PMC5488362
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