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BRIE

BRIE

BRIE (Bayesian regression for isoform estimation) is a tool to quantify splicing from RNA-seq data. The BRIE algorithm learns prior distribution isoform proportions from the sequences in samples using a Bayesian hierarchical model.

Topic

Genetic variation; RNA-seq; RNA splicing

Details

  • Operation: Genetic variation analysis
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Apache-2.0
  • Cost: Free
  • Version name: 0.1.1
  • Maturity: Emerging
  • Credit: European Research Council, University of Edinburgh.
  • Contact: Yuanhua Huang Y.Huang _at_ ed.ac.uk
  • Collection: -

Publications

Huang Y, Sanguinetti G "BRIE: transcriptome-wide splicing quantification in single cells." Genome Biol. 2017 Jun 27;18(1):123. https://doi.org/10.1186/s13059-017-1248-5
PMID: 28655331
PMCID: PMC5488362


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