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Citrus

Citrus

Citrus is a tool for deducing of confounding effects in single-cell RNA-seq data. The Citrus algorithm uses a new statistical technique, single-cell partial least squares (scPLS).

Topic

Gene expression; RNA-seq

Details

  • Operation: Sequencing quality control; RNA-Seq analysis
  • Software interface: Command-line user interface; Library
  • Language: C++;R
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: GNU GPL v=>2
  • Cost: Free
  • Version name: 0.99
  • Maturity: Emerging
  • Credit: The National Institutes of Health (NIH), the Michigan Center for Single-Cell Genomic Data Analytics–part of the Michigan Institute for Data Science (MIDAS).
  • Contact: Mengjie Chen mengjie _at_ email.unc.edu
  • Collection: -

Publications

Chen M, Zhou X "Controlling for Confounding Effects in Single Cell RNA Sequencing Studies Using both Control and Target Genes." Sci Rep. 2017 Oct 19;7(1):13587. https://doi.org/10.1038/s41598-017-13665-w
PMID: 29051597
PMCID: PMC5648789


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