CrossHub is a tool for the analysis of methylome data using The Cancer Genome Atlas (TCGA). CrossHub identifies possible transcription factor gene (TF-gene) interactions. The CrossHub algorithm has RNA-Seq analysis functions for differential expression analysis, prediction of regulatory TF and miRNA, analysis of methylation profiles, and RNA-Seq vs. clinical (TNM, stage, follow-up) correlation analysis.
Gene expression; Genomics; Oncology; RNA-seq
Krasnov GS, Dmitriev AA, Melnikova NV, Zaretsky AR, Nasedkina TV, Zasedatelev AS, Senchenko VN, Kudryavtseva AV "CrossHub: a tool for multi-way analysis of The Cancer Genome Atlas (TCGA) in the context of gene expression regulation mechanisms." Nucleic Acids Res. 2016; 44(7):e62 https://doi.org/10.1093/NAR/GKV1478
PMID: 26773058
PMCID: PMC4838350
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