DPre (driver-predictor) is a tool to identify bias in differentiation and genes affecting cell type conversions in Single-cell RNA-seq (scRNA-seq) data. The DPre algorithm scores transcriptional similarity of each gene between data sets to estimate differentiation biases.
RNA-seq; Gene expression
Steffens S, Fu X, He F, Li Y, Babarinde IA, Hutchins AP "DPre: Computational Identification of Differentiation Bias and Genes Underlying Cell Type Conversions" Bioinformatics. 2019 Oct 17;btz789. https://doi.org/10.1093/bioinformatics/btz789
PMID: 31621827
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