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LAmbDA

LAmbDA

LAmbDA is a tool for single-cell RNA-seq (scRNA-seq) data. The LAmbDA algorithm uses a transfer technique model to train models to decrease batch effects.

Topic

RNA-seq; Transcriptomics

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Maturity: Stable
  • Credit: National Institutes of Health NLM-MIDASTraining Fellowship, National Institutes of Health NLM-NRSA Fellowship, Indiana University School of Medicine (Indianapolis, IN).
  • Contact: Kun Huang kunhuang _at_ iu.edu | Jie Zhang jizhan _at_ iu.edu
  • Collection: -

Publications

Johnson TS, Wang T, Huang Z, Yu CY, Wu Y, Han Y, Zhang Y, Huang K, Zhang J "LAmbDA: label ambiguous domain adaptation dataset integration reduces batch effects and improves subtype detection." Bioinformatics. 2019 Nov 1;35(22):4696-4706. https://doi.org/10.1093/bioinformatics/btz295
PMID: 31038689
PMCID: PMC6853662


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