LIGER (Linked Inference of Genomic Experimental Relationships) is a tool for the analysis of multiple single-cell RNA-seq (scRNA-seq) data sets. The LIGER algorithm uses integrative non-negative matrix factorization to identify factors shared among data sets.
RNA-Seq; Gene expression
Welch JD, Kozareva V, Ferreira A, Vanderburg C, Martin C, Macosko EZ "Single-Cell Multi-omic Integration Compares and Contrasts Features of Brain Cell Identity" Cell. 2019 Jun 13;177(7):1873-1887.e17. https://doi.org/10.1016/j.cell.2019.05.006
PMID: 31178122
PMCID: PMC6716797
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