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Net-RSTQ

Net-RSTQ

Net-RSTQ is a tool to quantify isoforms in RNA-seq data aimed for cancer transcriptome. The Net-RSTQ algorithm uses protein domain-domain interaction network information as prior knowledge in the abundance estimation.

Topic

RNA-Seq; Transcriptomics; Oncology; Gene transcripts

Details

  • Operation: Gene expression profiling
  • Software interface: Command-line user interface
  • Language: MATLAB
  • Operating system: Linux; Microsoft Windows
  • License: Apache License 2.0
  • Cost: -
  • Version name: -
  • Credit: National Science Foundation (NSF).
  • Contact: Rui Kuang kuang _at_ cs.umn.edu
  • Collection: -

Publications

Zhang W, Chang JW, Lin L, Minn K, Wu B, Chien J, Yong J, Zheng H, Kuang R "Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis." PLoS Comput. Biol. 2015; 11(12):e1004465 https://doi.org/10.1371/journal.pcbi.1004465
PMID: 26699225
PMCID: PMC4689380


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