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PLNseq
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PLNseq

PLNseq is a tool for the differential gene expression analysis (DGE) in RNA-seq data. The PLNseq algorithm uses a multivariate Poisson lognormal distribution for modeling the read count data.



PLNseq

PLNseq is a tool for the differential gene expression analysis (DGE) in RNA-seq data. The PLNseq algorithm uses a multivariate Poisson lognormal distribution for modeling the read count data.

Topic

Sequencing; RNA-Seq; RNA

Details

  • Operation: RNA-seq analysis; Gene expression analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU General Public License v>=2
    • Cost: Free
  • Version name: 1.0
    • Maturity: Stable
  • Credit: -
  • Contact: Hong Zhang zhanghfd _at_ fudan.edu.cn
  • Collection: -

Publications

Zhang H, Xu J, Jiang N, Hu X, Luo Z "PLNseq: a multivariate Poisson lognormal distribution for high-throughput matched RNA-sequencing read count data." Stat Med 2015; 34(9):1577-89 https://doi.org/10.1002/sim.6449
PMID: 25641202


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