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SARTools

SARTools

SARTools is an R tool package for differential expression analysis of RNA-seq data. SARTools uses DESeq2 and edgeR. The input consists of raw count data, experimental description files. It will then normalize, estimate dispersion, and analyze differential gene expression. The output is a tab-delimited file and optionally a report in HTML format.

Topic

Statistics and probability; Transcriptomics

Details

  • Operation: Standardisation and normalisation; RNA-seq read count analysis; Differential gene expression analysis
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU GPL v2
  • Cost: Free
  • Version name: 1.7.1
  • Maturity: Stable
  • Credit: The France Génomique National infrastructure, "Investissements d’Avenir", the Agence Nationale pour la Recherche.
  • Contact: Hugo Varet hugo.varet _at_ pasteur.fr | Jean-Yves Coppée jean-yves.coppee _at_ pasteur.fr | Marie-Agnès Dillies marie-agnes.dillies _at_ pasteur.fr
  • Collection: -

Publications

Varet H, Brillet-Gueguen L, Coppee JY, Dillies MA "SARTools: A DESeq2- and EdgeR-Based R Pipeline for Comprehensive Differential Analysis of RNA-Seq Data." PLoS One. 2016 Jun 9;11(6):e0157022. eCollection 2016. https://doi.org/10.1371/journal.pone.0157022
PMID: 27280887
PMCID: PMC4900645


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