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SCALE

SCALE

SCALE is a tool to model allele-specific gene expression in single-cell RNA-seq (scRNA-seq) data. SCALE identifies genes displaying allelic differences in bursting parameters and genes whose alleles not burst independently.

Topic

RNA-Seq; Gene expression

Details

  • Operation: RNA-seq analysis
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: -
  • Credit: National Institutes of Health (NIH).
  • Contact: Yuchao Jiang yuchaoj _at_ email.unc.edu | nzh _at_ wharton.upenn.edu | mingyao _at_ mail.med.upenn.edu | nzh _at_ wharton.upenn.edu
  • Collection: -

Publications

Jiang Y, Zhang NR, Li M "SCALE: modeling allele-specific gene expression by single-cell RNA sequencing." Genome Biol 18(1): 74. https://doi.org/10.1186/s13059-017-1200-8
PMID: 28446220
PMCID: 28446220


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