SLICER (Selective Locally Linear Inference of Cellular Expression Relationships) is a tool to compute cell trajectories during expression changes in RNA-seq data. The SLICER algorithm detects non-linear expression changes, detect branching, loop components, and their number and locations.
RNA-seq; Gene expression
Welch JD, Hartemink AJ, Prins JF "SLICER: inferring branched, nonlinear cellular trajectories from single cell RNA-seq data." Genome Biol. 2016 May 23;17(1):106. https://doi.org/10.1186/s13059-016-0975-3
PMID: 27215581
PMCID: PMC4877799
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