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SpatialDE

SpatialDE

SpatialDE is a tool to identify spatially variable genes in data from multiplexed imaging or RNA-seq data. The SpatialDE algorithm can cluster genes for expression-based tissue histology.

Topic

Gene expression; Statistics and probability; RNA-seq; Data mining

Details

  • Operation: Statistical modelling; Expression data visualisation; Network simulation; Gene expression profiling
  • Software interface: Command-line user interface
  • Language: R, Python
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: The MIT licence
  • Cost: Free
  • Version name: 0.1.0
  • Credit: The European Molecular Biology Laboratory (EMBL), the Wellcome Trust, ERC Consolidator Grant ThDEFINE, the EU.
  • Contact: Valentine Svensson vale _at_ ebi.ac.uk | Oliver Stegle oliver.stegle _at_ ebi.ac.uk,
  • Collection: -

Publications

Svensson V, Teichmann SA, Stegle O "SpatialDE: identification of spatially variable genes." Nat. Methods 2018; 15(5):343-346 https://doi.org/10.1038/nmeth.4636
PMID: 29553579
PMCID: PMC6350895


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