Vireo (Variational Inference for Reconstructing Ensemble Origin) is a tool to demultiplex pooled single-cell RNA-seq (scRNA-seq) data. The Vireo algorithm uses a Bayesian approach and works with data where only partial or no genotype information exists.
RNA-seq; Gene expression; Transcriptomics
Huang Y, McCarthy DJ, Stegle O "Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference." Genome Biol. 2019 Dec 13;20(1):273. https://doi.org/10.1186/s13059-019-1865-2
PMID: 31836005
PMCID: PMC6909514
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