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clusterProfiler

clusterProfiler

clusterProfiler is an R tool for the enrichment analysis and visualization of gene clusters. The clusterProfiler algorithm uses Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases.

Topic

Genetics; Data visualisation

Details

  • Operation: Gene-set enrichment analysis; Statistical calculation
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Artistic-2.0
  • Cost: Free
  • Version name: 3.14.0
  • Maturity: Mature
  • Credit: National “973” Projects of China, the 2007 Chang-Jiang Scholars Program, “211” Projects, National Natural Science Foundation of China, Guangdong Natural Science Research Grant, the Fundamental Research Funds for the Central Universities.
  • Contact: Guangchuang Yu guangchuangyu _at_ gmail.com
  • Collection: Bioconductor

Publications

Yu G, Wang LG, Han Y, He QY "clusterProfiler: an R package for comparing biological themes among gene clusters." OMICS. 2012 May;16(5):284-7. https://doi.org/10.1089/omi.2011.0118
PMID: 22455463
PMCID: PMC3339379


Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J1, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M "Orchestrating high-throughput genomic analysis with Bioconductor." Nat Methods. 2015 Feb;12(2):115-21. https://doi.org/10.1038/nmeth.3252
PMID: 25633503
PMCID: PMC4509590


Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. "Bioconductor: open software development for computational biology and bioinformatics." Genome Biol. 2004;5(10):R80. Epub 2004 Sep 15. https://doi.org/10.1186/gb-2004-5-10-r80
PMID: 15461798
PMCID: PMC545600


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