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g:Profiler

g:Profiler

g:Profiler is a web-based tool for gene enrichment analysis of gene ontologies, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and protein-protein interaction analyses. g:Profiler updates Ensembl data quarterly. An R client is available and it includes the following four tools: 1. g:GOSt for functional enrichment analysis and visualization, 2. g:Convert for identifier conversion, 3. g:Orth for orthology searching, and 4. g:SNPense for Single nucleotide polymorphism (SNP) mapping by 'rs' identifiers.

Topic

Ontology and terminology; Function analysis; Genomics; Molecular interactions, pathways and networks

Details

  • Operation: Data retrieval; Enrichment analysis; Pathway or network analysis; Gene functional annotation
  • Software interface: Web user interface; command-line user interface
  • Language: R;Python;Javascript
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU General Public License v>=2
  • Cost: Free
  • Version name: 0.1.7
  • Maturity: Mature
  • Credit: Estonia’s Integration to the European Bioinformatics Infrastructure (ELIXIR); European Union through the Structural Fund, European Regional Development Fund for CoE of Estonian ICT research EXCITE projects.
  • Contact: biit.support _at_ ut.ee | Liis Kolberg liis.kolberg _at_ ut.ee
  • Collection: -

Publications

Reimand J, Arak T, Adler P, Kolberg L, Reisberg S, Peterson H, Vilo J "g:Profiler-a web server for functional interpretation of gene lists (2016 update)." Nucleic Acids Res. 2016 Jul 8;44(W1):W83-9. Apr 20. https://doi.org/10.1093/nar/gkw199
PMID: 27098042
PMCID: PMC4987867


Reimand J, Kull M, Peterson H, Hansen J, Vilo J "g:Profiler--a web-based toolset for functional profiling of gene lists from large-scale experiments." Nucleic Acids Res. 2007 Jul;35(Web Server issue):W193-200. Epub 2007 May 3. https://doi.org/10.1093/nar/gkm226
PMID: 17478515
PMCID: PMC1933153


Reimand J, Arak T, Vilo J "g:Profiler--a web server for functional interpretation of gene lists (2011 update)." Nucleic Acids Res. 2011 Jul;39(Web Server issue):W307-15 https://doi.org/10.1093/nar/gkr378
PMID: 21646343
PMCID: PMC3125778


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