sSeq is a tool for differential gene expression (DGE) analysis using RNA-seq data. The sSeq algorithm uses the Negative Binomial (NB) distribution, and a shrinkage technique, and outputs expression as counts.
Gene expression; RNA-Seq
Yu D, Huber W, Vitek O "Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size." Bioinformatics 2013; 29(10):1275-82 https://doi.org/10.1093/bioinformatics/btt143
PMID: 23589650
PMCID: PMC3654711
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