13Check_RNA

13Check_RNA evaluates and corrects systematic errors in 13C chemical shift (CS) assignments of RNA to improve the accuracy of structural information derived from chemical shifts.

Key Features:

• Error Correction: Implements an existing method to identify and correct systematic errors in 13C chemical shift (CS) assignments of RNA.
• Output Formats: Produces results in NMR-STAR format for integration with NMR data workflows and databases.
• Implementation: Implemented as a Python module.

Scientific Applications:

• Structural biology: Provides corrected 13C CS assignments to improve the reliability of RNA structural analyses.
• Data curation and deposition: Supports re-referencing and correction of 13C CS data prior to deposition into the Biological Magnetic Resonance Data Bank (BMRB).

Methodology:

Builds upon an existing method to systematically identify and correct errors in 13C chemical shift data for RNA by recalibrating CS values.