2019nCoVAS

2019nCoVAS analyzes SARS-CoV-2 genomic data, predicts epidemic transmission trends, and evaluates population psychological stress associated with the COVID-19 pandemic.


Key Features:

  • Epidemic Transmission Prediction: Applies computational and statistical models to forecast COVID-19 transmission dynamics using epidemiological data.
  • LAUP Genome Analysis: Performs Lineage-Associated Underrepresented Permutation (LAUP) analysis to investigate mutation patterns and lineage diversification in SARS-CoV-2 genomes.
  • Psychological Stress Evaluation: Assesses public psychological stress during the COVID-19 pandemic using a specialized emotional dictionary developed for COVID-19-related contexts.

Scientific Applications:

  • Epidemiological Modeling: Supports prediction of SARS-CoV-2 transmission patterns for outbreak analysis and intervention planning.
  • Viral Genomics: Enables investigation of SARS-CoV-2 mutation dynamics and lineage evolution using genome sequence analysis.
  • Public Health Psychology: Facilitates assessment of psychological stress responses associated with the COVID-19 pandemic.

Methodology:

The platform applies statistical transmission prediction models to epidemiological data, performs Lineage-Associated Underrepresented Permutation (LAUP) analysis on SARS-CoV-2 genome sequences, and evaluates psychological stress using a COVID-19–specific emotional dictionary applied to text-based data.

Topics

Collections

Details

Tool Type:
web application
Added:
3/19/2021
Last Updated:
11/24/2024

Operations

Data Inputs & Outputs

Modelling and simulation

Publications

Xiao M, Liu G, Xie J, Dai Z, Wei Z, Ren Z, Yu J, Zhang L. 2019nCoVAS: Developing the Web Service for Epidemic Transmission Prediction, Genome Analysis, and Psychological Stress Assessment for 2019-nCoV. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2021;18(4):1250-1261. doi:10.1109/tcbb.2021.3049617. PMID:33406042. PMCID:PMC8769043.

PMID: 33406042
PMCID: PMC8769043
Funding: - National Science and Technology Major Project: 2018ZX10201002 - China Postdoctoral Science Foundation: 2020M673221 - Sichuan University Postdoctoral Research and Development Foundation: 2020SCU12056