3DCNN
3DCNN performs protein model quality assessment using 3D convolutional neural networks to evaluate local structural accuracy at the residue level.
Key Features:
- Local Structure Quality Assessment: Evaluates individual residues to identify local inaccuracies, enabling granular analysis of model quality.
- Deep Learning Architecture: Utilizes 3D convolutional networks to capture spatial hierarchies and complex patterns in protein structures.
- Single-Model Methodology: Analyzes individual models directly, avoiding reliance on ensemble approaches for efficiency and precision.
Scientific Applications:
- Protein Structure Prediction: Enhances selection of high-quality models from computational predictions by assessing residue-level accuracy.
Methodology:
3DCNN performs local quality evaluation of each residue and integrates these assessments to form a comprehensive view of the protein structure's accuracy.
Topics
Details
- License:
- MIT
- Tool Type:
- command-line tool
- Programming Languages:
- Python
- Added:
- 11/14/2019
- Last Updated:
- 1/11/2021
Operations
Publications
Sato R, Ishida T. Protein model accuracy estimation based on local structure quality assessment using 3D convolutional neural network. PLOS ONE. 2019;14(9):e0221347. doi:10.1371/journal.pone.0221347. PMID:31487288. PMCID:PMC6728020.