3DCNN

3DCNN performs protein model quality assessment using 3D convolutional neural networks to evaluate local structural accuracy at the residue level.


Key Features:

  • Local Structure Quality Assessment: Evaluates individual residues to identify local inaccuracies, enabling granular analysis of model quality.
  • Deep Learning Architecture: Utilizes 3D convolutional networks to capture spatial hierarchies and complex patterns in protein structures.
  • Single-Model Methodology: Analyzes individual models directly, avoiding reliance on ensemble approaches for efficiency and precision.

Scientific Applications:

  • Protein Structure Prediction: Enhances selection of high-quality models from computational predictions by assessing residue-level accuracy.

Methodology:

3DCNN performs local quality evaluation of each residue and integrates these assessments to form a comprehensive view of the protein structure's accuracy.

Topics

Details

License:
MIT
Tool Type:
command-line tool
Programming Languages:
Python
Added:
11/14/2019
Last Updated:
1/11/2021

Operations

Publications

Sato R, Ishida T. Protein model accuracy estimation based on local structure quality assessment using 3D convolutional neural network. PLOS ONE. 2019;14(9):e0221347. doi:10.1371/journal.pone.0221347. PMID:31487288. PMCID:PMC6728020.

PMID: 31487288
PMCID: PMC6728020
Funding: - Japan Society for the Promotion of Science: 18K11524