Arteria

Arteria automates orchestration and execution of sequencing data processing using an event-driven, workflow-based architecture with RESTful micro-services to manage data from raw acquisition to final analysis for massive parallel sequencing technologies.


Key Features:

  • Event-Driven Automation: Employs an event-driven model that triggers and orchestrates tasks in response to specific events during sequencing data management.
  • Modular Micro‑service Architecture: Uses a modular design that integrates bioinformatic micro-services to provide flexibility and scalability.
  • Workflow-Based Process Management: Models sequencing data handling as defined workflows covering steps from raw data acquisition to final analysis.
  • RESTful Micro‑services for Execution: Implements execution through RESTful micro-services, enabling independent component development and maintenance.
  • Implementation Language: Written primarily in Python.

Scientific Applications:

  • Sequencing core facility deployment: Implemented in three sequencing core facilities to automate data handling, reduce manual intervention, and minimize errors.
  • High-throughput sequencing data management: Manages and accelerates throughput for large volumes of data generated by massive parallel sequencing technologies.

Methodology:

The methodology comprises three conceptual levels: orchestration using an event-based automation model, process definition by modeling sequencing data processing as workflows, and execution via RESTful micro‑services.

Topics

Details

License:
MIT
Programming Languages:
Python
Added:
1/14/2020
Last Updated:
12/2/2020

Operations

Publications

Dahlberg J, Hermansson J, Sturlaugsson S, Lysenkova M, Smeds P, Ladenvall C, Guimera RV, Reisinger F, Hofmann O, Larsson P. Arteria: An automation system for a sequencing core facility. GigaScience. 2019;8(12). doi:10.1093/gigascience/giz135. PMID:31825479. PMCID:PMC6905352.

PMID: 31825479
PMCID: PMC6905352
Funding: - National Health and Medical Research Council: GNT1113531 - Uppsala University Hospital: ALF-717721

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