BEL Commons

BEL Commons provides an environment to explore, analyze, curate, and integrate Biological Expression Language (BEL) networks to support systems- and network-biology knowledge discovery.


Key Features:

  • File Management: Uploads BEL-format files which are parsed, validated, compiled, and stored with fine-grained permissions.
  • Network Exploration and Sharing: Summarizes and explores BEL networks and supports sharing of networks for collaborative use.
  • Query Builder: Constructs targeted queries to locate relevant subgraphs and relationships within large BEL networks.
  • Visualization Interface: Renders and enables interactive examination of network structures and relationships.
  • Analytical Services: Provides integrated data-driven analysis on knowledge networks to support hypothesis generation.

Scientific Applications:

  • Systems Biology: Enables integrative management and analysis of BEL-encoded networks for systems- and network-biology research.
  • Genomics and Proteomics: Supports interpretation of network interactions relevant to genomics and proteomics studies.
  • Hypothesis Generation: Facilitates deriving insights and generating hypotheses from complex biological networks.

Methodology:

Parses, validates, compiles, and stores BEL-format files; supports network summarization, exploration, query construction, visualization, and integrated analytical services.

Topics

Details

License:
MIT
Maturity:
Mature
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Python
Added:
8/11/2019
Last Updated:
6/16/2020

Operations

Publications

Hoyt CT, Domingo-Fernández D, Hofmann-Apitius M. BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database. 2018;2018. doi:10.1093/database/bay126. PMID:30576488. PMCID:PMC6301338.

PMID: 30576488
PMCID: PMC6301338
Funding: - European Federation of Pharmaceutical Industries and Associations: 115568 - Seventh Framework Programme: FP7/2007-2013

Documentation

Downloads

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