CDMetaPOP

CDMetaPOP models multilocus selection in a spatially-explicit, individual-based landscape genetics framework to simulate genotype–environment associations and evolutionary dynamics across complex landscapes.

Key Features:

• Integration with CDPOP/CDMetaPOP: Integrates with the landscape genetics programs CDPOP and CDMetaPOP to extend landscape-level individual-based simulation capabilities.
• Multivariate Environmental Gradients: Implements multivariate environmental gradients using a linear additive model to evaluate genotype–environment associations across loci.
• Simulation of Multilocus Selection: Simulates selection across any number of loci influenced by multiple environmental variables within individuals in space.
• Validation and Evaluation: Validated using individual-based selection simulations under Wright–Fisher assumptions and evaluated across simple to complex selection scenarios.
• Complex Landscape Simulations: Simulates multilocus selection across complex landscapes including linked loci and spatially varying environmental variables.
• Gene Flow and Selection Interactions: Quantifies contributions and interactions between gene flow and selection-driven processes across multivariate landscapes.

Scientific Applications:

• Landscape genetics: Models how spatially varying environmental factors drive genetic variation and structure across landscapes.
• Population viability: Assesses how multilocus selection and landscape processes influence population persistence and evolutionary trajectories.
• Adaptation to environmental change: Evaluates genotype–environment associations to study adaptive responses to changing conditions.
• Habitat fragmentation effects: Investigates impacts of habitat fragmentation on gene flow, selection, and multilocus evolutionary dynamics.

Methodology:

Uses an individual-based eco-evolutionary model in a spatially-explicit framework that simulates multilocus selection and genotype–environment associations via linear additive models, with validation under Wright–Fisher assumptions.