CytoMegaloVirus DataBase (CMVdb)

CytoMegaloVirus DataBase (CMVdb) aggregates and harmonizes omics, genomic, strain, protein, and drug information for human cytomegalovirus (CMV), a double-stranded DNA virus of the herpesvirus family, to support comparative and translational CMV research.

Key Features:

• Comprehensive Data Integration: Integrates datasets from public biological databases, virus taxonomy databanks, viral databases, and drug banks into a harmonized repository.
• Detailed Strains and Genomics: Provides strain-level metadata, gene annotations, expressed protein records, and genomic sequences for CMV.
• Therapeutic Data: Includes curated information on drugs used for treating cytomegalovirus infections and associated drug-related metadata.
• In-House Data Analysis: Performs in-house processing and analysis of aggregated CMV omics and genomic data.

Scientific Applications:

• Comparative Genomics: Enables analysis of CMV genetic diversity and strain relationships using genomic sequences and gene/protein annotations.
• Pathogenesis and Immunology: Supports investigation of CMV gene and protein functions relevant to immune evasion and disease, including studies in immunocompromised patients.
• Therapeutic Development: Facilitates identification and evaluation of antiviral compounds and drug–target relationships for CMV.

Methodology:

Aggregates and harmonizes datasets from public biological, virus taxonomy, viral, and drug databases and performs in-house processing of the integrated omics, genomic, strain, protein, and drug data.