CoreSlicer

CoreSlicer extracts and measures morphomic markers from computed tomography (CT) images to quantify body composition biomarkers.

Key Features:

• Morphomic marker extraction: Performs extraction and measurement of morphomic markers from CT images.
• Muscle and fat composition quantification: Measures muscle and fat composition from CT-derived morphomic markers.
• DICOM data handling: Includes DICOM viewing tools for handling CT image data.
• Extensible plugin interface: Provides an extensible plugin interface to develop and validate new morphomic markers.
• Validation against reference software: Published validation studies report high agreement between CoreSlicer measurements and established reference software.

Scientific Applications:

• Operative risk prediction (cardiovascular): Supports operative risk prediction across cardiovascular patient populations using CT-derived morphomic markers.
• Body composition biomarker research: Enables quantification of body composition biomarkers from CT for clinical and translational studies.
• Method development and validation: Facilitates development and validation of new morphomic markers through plugin workflows and comparison to reference software.

Methodology:

Extraction and measurement of morphomic markers from CT DICOM images using built-in DICOM viewing tools and an extensible plugin interface, with validation via comparison to established reference software.