CrystFEL

CrystFEL processes serial crystallography diffraction data from X-ray free-electron lasers (XFEL) and synchrotron sources to reconstruct and analyze diffraction images for determination of atomic structures of biomolecules.

Key Features:

• Serial Crystallography Data Processing: Handles diffraction data from serial femtosecond crystallography (SFX) experiments and other serial crystallography datasets collected at XFEL and synchrotron sources.

Scientific Applications:

• Structural Biology: Reconstruction and analysis of atomic structures of proteins, nucleic acids, and other biomolecules from serial diffraction data.
• Time-Resolved Studies: Enables analysis of time-resolved SFX datasets from XFEL sources to observe molecular changes over time.

Methodology:

Employs advanced algorithms to process raw diffraction images, with methodology grounded in theoretical frameworks and algorithmic rationale described in primary publications.