DisV-HPV16

DisV-HPV16 analyzes Human Papillomavirus type 16 (HPV16) oncogene expression from RNA sequencing data to detect viral infection status and characterize virus–host gene expression dynamics in HPV16-associated cancers.


Key Features:

  • Rapid Detection: Performs rapid detection of HPV16 and quantification of its oncogene expression from RNA sequencing data.
  • Customizable Reference Files: Supports modification of reference files to enable identification of candidate viruses.
  • High Reliability and Accuracy: Empirical laboratory experiments have confirmed its accuracy and reliability for HPV16 oncogene expression analysis.
  • Comprehensive Insights: Analyzes RNA sequencing data to infer viral infection status and compare expression dynamics between viral and host genes.

Scientific Applications:

  • Cancer Research: Enables investigation of HPV16 genetic elements that contribute to carcinogenesis.
  • Oncogene Expression Evaluation: Facilitates evaluation of HPV16 oncogene expression levels to study tumor progression and malignancy.

Methodology:

Leverages high-throughput RNA sequencing data to detect viral infection events, assess genome integration, and evaluate HPV16 oncogene expression.

Topics

Details

License:
Unlicense
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Mac
Programming Languages:
Shell
Added:
8/3/2019
Last Updated:
6/16/2020

Operations

Publications

Yan B, Liu X, Zhang S, Yu S, Tong F, Xie H, Song L, Zhang Y, Wei L. DisV-HPV16, versatile and powerful software to detect HPV in RNA sequencing data. BMC Infectious Diseases. 2019;19(1). doi:10.1186/s12879-019-4123-z. PMID:31142265. PMCID:PMC6542142.

PMID: 31142265
PMCID: PMC6542142
Funding: - Natural Science Foundation of China: 81501737, 81672670 - Heilongjiang province outstanding youth foundation: jc2018023

Links