DisV-HPV16
DisV-HPV16 analyzes Human Papillomavirus type 16 (HPV16) oncogene expression from RNA sequencing data to detect viral infection status and characterize virus–host gene expression dynamics in HPV16-associated cancers.
Key Features:
- Rapid Detection: Performs rapid detection of HPV16 and quantification of its oncogene expression from RNA sequencing data.
- Customizable Reference Files: Supports modification of reference files to enable identification of candidate viruses.
- High Reliability and Accuracy: Empirical laboratory experiments have confirmed its accuracy and reliability for HPV16 oncogene expression analysis.
- Comprehensive Insights: Analyzes RNA sequencing data to infer viral infection status and compare expression dynamics between viral and host genes.
Scientific Applications:
- Cancer Research: Enables investigation of HPV16 genetic elements that contribute to carcinogenesis.
- Oncogene Expression Evaluation: Facilitates evaluation of HPV16 oncogene expression levels to study tumor progression and malignancy.
Methodology:
Leverages high-throughput RNA sequencing data to detect viral infection events, assess genome integration, and evaluate HPV16 oncogene expression.
Topics
Details
- License:
- Unlicense
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Mac
- Programming Languages:
- Shell
- Added:
- 8/3/2019
- Last Updated:
- 6/16/2020
Operations
Publications
Yan B, Liu X, Zhang S, Yu S, Tong F, Xie H, Song L, Zhang Y, Wei L. DisV-HPV16, versatile and powerful software to detect HPV in RNA sequencing data. BMC Infectious Diseases. 2019;19(1). doi:10.1186/s12879-019-4123-z. PMID:31142265. PMCID:PMC6542142.
PMID: 31142265
PMCID: PMC6542142
Funding: - Natural Science Foundation of China: 81501737, 81672670
- Heilongjiang province outstanding youth foundation: jc2018023
Links
Issue tracker
https://github.com/ybq1204/DisV-HPV16/issues