DiscoRhythm

DiscoRhythm (Discovering Rhythmicity) is a user-friendly application for characterizing rhythmicity in temporal biological data, which is available as a web application or an R/Bioconductor package. The tool allows users to estimate phase, amplitude, and statistical significance using four popular approaches to rhythm detection, and has been optimized for speed to enable rapid analysis of -omic-scale datasets in real-time. DiscoRhythm also provides informative visualizations, interactive modules for quality control, dimensionality reduction, periodicity profiling, and incorporation of experimental replicates, making it a thorough toolkit for analyzing rhythmicity.

Topic

Phasing;Essential dynamics;Visualisation

Detail

  • Operation: Data input; Statistical analysis; Visualization; Quality control; Dimensionality reduction; Periodicity profiling; Execution time optimization

  • Software interface: Web application,Library

  • Language: R

  • License: GNU General Public Licence v3

  • Cost: Free

  • Version name: -

  • Credit: Lithuanian Science Foundation, the Canadian Institutes of Health Research, the National Institute of Mental Health [1R01MH105409-01], Brain Canada and CAMH Foundation, the Krembil. Foundation.

  • Input: -

  • Output: -

  • Contact: art.petronis@camh.ca, gabriel.oh@camh.ca

  • Collection: -

  • Maturity: Stable

Publications

  • DiscoRhythm: an easy-to-use web application and R package for discovering rhythmicity.
  • Carlucci M, et al. DiscoRhythm: an easy-to-use web application and R package for discovering rhythmicity. DiscoRhythm: an easy-to-use web application and R package for discovering rhythmicity. 2019; 36:1952-4. doi: 10.1093/bioinformatics/btz834
  • https://doi.org/10.1093/bioinformatics/btz834
  • PMID: 31702788
  • PMC: -

Download and documentation

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