Divergence

Divergence is an R package designed to analyze high-dimensional omics data, offering a unique approach to transform each entry in a profile into a digitized (binary or ternary) code based on its deviation from a specified baseline population. This innovative framework distinguishes itself from existing methods by allowing the digitization of continuous omics data at the univariate or multivariate level.

Topic

Metagenomics;RNA-Seq;Microarray experiment

Detail

  • Operation: Essential dynamics;Expression analysis

  • Software interface: Library

  • Language: R

  • License: GNU General Public License, version 2

  • Cost: Free

  • Version name: 1.18.0

  • Credit: NIH-NCI, the Department of Defense (DoD) office of the Congressionally Directed Medical Research Programs (CDMRP).

  • Input: -

  • Output: -

  • Contact: Wikum Dinalankara wdd4001@med.cornell.edu, Luigi Marchionni marchion@jhu.edu

  • Collection: -

  • Maturity: Stable

Publications

  • An R package for divergence analysis of omics data
  • Dinalankara W, Ke Q, Geman D, Marchionni L. An R package for divergence analysis of omics data. PLoS One. 2021 Apr 5;16(4):e0249002. doi: 10.1371/journal.pone.0249002. PMID: 33819273; PMCID: PMC8021195.
  • https://doi.org/10.1371/journal.pone.0249002
  • PMID: 33819273
  • PMC: PMC8021195

Download and documentation


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