FlowSculpt

FlowSculpt computes optimal pillar sequences and inlet designs to sculpt cross-sectional shapes of inertially flowing microfluidic streams using sequences of bluff-body structures for inverse design of passive flow control.


Key Features:

  • Pillar sequence and inlet optimization: Determines optimal pillar sequences and inlet designs to produce specified cross-sectional flow shapes in inertial microfluidic flows around bluff-body structures.
  • Customizable genetic algorithm: Uses a customizable genetic algorithm that iteratively searches an extensive design space to identify configurations matching target flow shapes.
  • Multi-material design capabilities: Supports multi-material designs enabling spatial variation in pillar properties.
  • Half-height pillar symmetry-breaking: Implements half-height pillars to enable symmetry-breaking deformations and expanded flow-shaping flexibility beyond full-height pillars.
  • Fast simulation method: Employs an extremely fast simulation method achieving a reported 34-fold reduction in runtime compared to traditional methods.
  • Enhanced search for input drawings: Includes enhanced search operations to design flow shapes that closely replicate user-provided input drawings.
  • Passive flow control focus: Targets passive flow control via sequences of bluff-body structures to manipulate inertially dominated microfluidic streams.

Scientific Applications:

  • Microfluidic device design: Designing complex flow-shaping microfluidic devices to produce target cross-sectional flow configurations.
  • Bioengineering: Applying flow-shaping designs in bioengineering contexts that require precise fluid manipulation.
  • Manufacturing: Supporting design of manufacturing processes that depend on controlled inertial microfluidic flows.
  • Chemistry: Enabling design of microfluidic systems for chemical applications that require specified flow shapes.

Methodology:

FlowSculpt applies a customizable genetic algorithm with iterative search across an extensive design space, evaluates candidate designs with an extremely fast simulation method (reported 34× speedup), performs enhanced searches to match input drawings, and supports multi-material and half-height pillar design options to optimize pillar sequences and inlet designs for inertial microfluidic flows around bluff-body structures.

Topics

Details

License:
MIT
Tool Type:
command-line tool, desktop application
Operating Systems:
Mac, Linux, Windows
Programming Languages:
C++, Python
Added:
11/14/2019
Last Updated:
12/29/2020

Operations

Publications

Stoecklein D, Davies M, de Rutte JM, Wu C, Di Carlo D, Ganapathysubramanian B. FlowSculpt: software for efficient design of inertial flow sculpting devices. Lab on a Chip. 2019;19(19):3277-3291. doi:10.1039/c9lc00658c. PMID:31482902.

PMID: 31482902
Funding: - National Science Foundation: 1149365, 1306866

Links