FluReassort

FluReassort catalogs genomic reassortments among influenza viruses to support analysis of their roles in the emergence and evolution of new influenza A virus strains.

Key Features:

• Manual curation: Data were compiled through manual curation of extensive literature references.
• Event catalog: Contains records of 204 reassortment events involving 56 influenza A virus subtypes from isolates collected in 37 countries.
• Phylogenetic analysis: Supports phylogenetic analyses using various parameters to explore genetic relationships and evolutionary pathways.
• Reassortment networks: Generates graphical reassortment networks that elucidate correlations and potential causal links among subtypes.
• Visualization and evolutionary analysis: Provides visualization and evolutionary analysis of genomic reassortments to interpret reassortment preferences among subtypes.

Scientific Applications:

• Evolutionary dynamics: Study the evolutionary dynamics of influenza viruses and the mechanisms driving the emergence of new strains.
• Reassortment preference analysis: Analyze subtype-specific reassortment preferences and correlations among influenza A subtypes.
• Public health research: Inform virology, epidemiology, and pandemic preparedness by providing curated reassortment data and evolutionary analyses.

Methodology:

Manual curation of literature sources, phylogenetic analyses using various parameters, and construction of graphical reassortment networks.