FoldamerDB

FoldamerDB compiles and annotates experimentally characterized peptidic foldamers, documenting their sequences, structures, and biological activities.


Key Features:

  • Curated Foldamer Repository: Contains data on 1319 peptidic foldamer species and 1018 reported biological activities extracted from over 160 research publications.
  • Sequence and Structure Annotations: Provides detailed annotations including foldamer sequences, structural conformations, and associated biological activities.

Scientific Applications:

  • Foldamer Design and Functional Analysis: Supports research on antimicrobial, anticancer, anti-HIV, and materials-related applications through access to structurally and functionally annotated foldamers.

Methodology:

FoldamerDB is manually curated from peer-reviewed literature, with systematic extraction and annotation of foldamer sequence, structural, and biological activity data to ensure accuracy and consistency.

Topics

Details

Tool Type:
web application
Added:
1/14/2020
Last Updated:
12/29/2020

Operations

Publications

Nizami B, Bereczki-Szakál D, Varró N, el Battioui K, Nagaraj VU, Szigyártó IC, Mándity I, Beke-Somfai T. FoldamerDB: a database of peptidic foldamers. Nucleic Acids Research. 2019. doi:10.1093/nar/gkz993. PMID:31686102. PMCID:PMC7145536.

PMID: 31686102
Funding: - Hungarian Academy of Sciences: LP2016-2 - National Competitiveness and Excellence Program: NVKP_16-1-2016-0007

Documentation

Links