FoldamerDB
FoldamerDB compiles and annotates experimentally characterized peptidic foldamers, documenting their sequences, structures, and biological activities.
Key Features:
- Curated Foldamer Repository: Contains data on 1319 peptidic foldamer species and 1018 reported biological activities extracted from over 160 research publications.
- Sequence and Structure Annotations: Provides detailed annotations including foldamer sequences, structural conformations, and associated biological activities.
Scientific Applications:
- Foldamer Design and Functional Analysis: Supports research on antimicrobial, anticancer, anti-HIV, and materials-related applications through access to structurally and functionally annotated foldamers.
Methodology:
FoldamerDB is manually curated from peer-reviewed literature, with systematic extraction and annotation of foldamer sequence, structural, and biological activity data to ensure accuracy and consistency.
Topics
Details
- Tool Type:
- web application
- Added:
- 1/14/2020
- Last Updated:
- 12/29/2020
Operations
Publications
Nizami B, Bereczki-Szakál D, Varró N, el Battioui K, Nagaraj VU, Szigyártó IC, Mándity I, Beke-Somfai T. FoldamerDB: a database of peptidic foldamers. Nucleic Acids Research. 2019. doi:10.1093/nar/gkz993. PMID:31686102. PMCID:PMC7145536.
DOI: 10.1093/NAR/GKZ993
PMID: 31686102
Funding: - Hungarian Academy of Sciences: LP2016-2
- National Competitiveness and Excellence Program: NVKP_16-1-2016-0007
Documentation
User manual
http://foldamerdb.ttk.hu/help.php