G3viz

G3viz visualizes genetic mutation data using lollipop-diagrams to illustrate translational effects of mutations in cancer genomics.

Key Features:

• Lollipop-diagrams: Generates lollipop-diagrams to represent the positional and translational effects of genetic mutations.
• R integration: Provides R package functions to produce and manipulate mutation visualizations.
• Annotation: Supports embedding mutation annotations and metadata within diagrams.
• Export of figures: Exports annotated lollipop-diagrams as publication-quality figures.
• JavaScript rendering engine: Uses the g3lollipop.js JavaScript library to support diagram rendering.

Scientific Applications:

• Cancer genomics visualization: Visualizes mutation distributions and translational impacts in cancer genomics datasets.
• Mutation interpretation and annotation: Assists identification of recurrent sites and annotation of translational consequences of variants.
• Figure generation for publication: Produces exportable figures for presentation and publication of mutation analyses.

Methodology:

G3viz generates lollipop-diagrams via an R interface and uses the g3lollipop.js JavaScript library to support rendering.