Genomicus-plants
Genomicus-plants provides synteny browsing and comparative genomics visualization across multiple plant genomes to analyze gene organization and reconstruct ancestral gene arrangements.
Key Features:
- Unlimited Genome Comparison: Represents and compares an unlimited number of plant genomes simultaneously.
- Multi-dimensional Genome Navigation: Supports linear navigation along chromosome axes, transversal comparisons across species, and chronological exploration through evolutionary time.
- Phylogenetic Context: Provides a broad phylogenetic perspective to visualize genomic data within an evolutionary framework.
- Ancestral Gene Organization Reconstruction: Includes reconstructed ancestral gene organizations to assist interpretation of gene order evolution.
- Synteny Map Construction from Public Genomes: Constructs synteny maps using publicly available full genome sequences.
Scientific Applications:
- Evolutionary history of gene organization: Analyze the evolutionary history of gene organization across diverse plant species.
- Conserved region identification: Identify conserved genomic regions and assess their potential functional significance.
- Inference of evolutionary events: Infer duplications, deletions, and rearrangements that have shaped current plant genomes.
Methodology:
Constructs synteny maps from publicly available full genome sequences and integrates phylogenetic data to reconstruct ancestral gene organizations.
Topics
Collections
Details
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- web application
- Added:
- 1/21/2020
- Last Updated:
- 6/16/2020
Operations
Data Inputs & Outputs
Dot plot plotting
Publications
Nguyen NTT, Vincens P, Roest Crollius H, Louis A. Genomicus 2018: karyotype evolutionary trees and on-the-fly synteny computing. Nucleic Acids Research. 2017;46(D1):D816-D822. doi:10.1093/nar/gkx1003. PMID:29087490. PMCID:PMC5753199.
Louis A, Nguyen NTT, Muffato M, Roest Crollius H. Genomicus update 2015: KaryoView and MatrixView provide a genome-wide perspective to multispecies comparative genomics. Nucleic Acids Research. 2014;43(D1):D682-D689. doi:10.1093/nar/gku1112. PMID:25378326. PMCID:PMC4383929.
Louis A, Muffato M, Roest Crollius H. Genomicus: five genome browsers for comparative genomics in eukaryota. Nucleic Acids Research. 2012;41(D1):D700-D705. doi:10.1093/nar/gks1156. PMID:23193262. PMCID:PMC3531091.
Muffato M, Louis A, Poisnel C, Crollius HR. Genomicus: a database and a browser to study gene synteny in modern and ancestral genomes. Bioinformatics. 2010;26(8):1119-1121. doi:10.1093/bioinformatics/btq079. PMID:20185404. PMCID:PMC2853686.
Louis A, Murat F, Salse J, Roest Crollius H. GenomicusPlants: A Web Resource to Study Genome Evolution in Flowering Plants. Plant and Cell Physiology. 2014;56(1):e4-e4. doi:10.1093/pcp/pcu177. PMID:25432975. PMCID:PMC4301744.
Downloads
- Biological dataftp://ftp.biologie.ens.fr/pub/dyogen/genomicus-plants/Genomicus-plants ftp download site providing reconstructed ancestral genomes with AGORA