Genomicus-fungi

Genomicus-fungi provides synteny-based comparative genomics visualization and analysis to study the evolution of gene organization across fungal species.


Key Features:

  • Multi-Dimensional Navigation: Provides linear chromosome-axis views, cross-species transverse comparisons, and chronological evolutionary time perspectives.
  • Unlimited Genome Comparison: Supports comparison of an unlimited number of genomes within a broad phylogenetic context.
  • Reconstructed Ancestral Gene Organization: Includes reconstructed ancestral gene organizations to interpret evolutionary events and genome-structure changes.
  • Synteny-Based Visualization: Implements synteny analysis to visualize and compare genomic regions across species.

Scientific Applications:

  • Evolution of Gene Organization: Investigating the evolution of gene organization within fungal species.
  • Phylogenetic Relationships: Inferring phylogenetic relationships across fungi using conserved synteny patterns.
  • Gene Conservation and Divergence: Identifying conserved genetic elements and divergence patterns across multiple species.
  • Ancestral Genome Interpretation: Reconstructing and interpreting ancestral genome structures to study historical genome changes.

Methodology:

Performs synteny analysis to visualize and compare genomic regions and integrates reconstructed ancestral gene organizations for evolutionary interpretation.

Topics

Collections

Details

Maturity:
Mature
Cost:
Free of charge
Tool Type:
web application
Added:
1/21/2020
Last Updated:
6/16/2020

Operations

Data Inputs & Outputs

Publications

Nguyen NTT, Vincens P, Roest Crollius H, Louis A. Genomicus 2018: karyotype evolutionary trees and on-the-fly synteny computing. Nucleic Acids Research. 2017;46(D1):D816-D822. doi:10.1093/nar/gkx1003. PMID:29087490. PMCID:PMC5753199.

Louis A, Nguyen NTT, Muffato M, Roest Crollius H. Genomicus update 2015: KaryoView and MatrixView provide a genome-wide perspective to multispecies comparative genomics. Nucleic Acids Research. 2014;43(D1):D682-D689. doi:10.1093/nar/gku1112. PMID:25378326. PMCID:PMC4383929.

Louis A, Muffato M, Roest Crollius H. Genomicus: five genome browsers for comparative genomics in eukaryota. Nucleic Acids Research. 2012;41(D1):D700-D705. doi:10.1093/nar/gks1156. PMID:23193262. PMCID:PMC3531091.

Muffato M, Louis A, Poisnel C, Crollius HR. Genomicus: a database and a browser to study gene synteny in modern and ancestral genomes. Bioinformatics. 2010;26(8):1119-1121. doi:10.1093/bioinformatics/btq079. PMID:20185404. PMCID:PMC2853686.

Downloads

Links

Service
https://www.genomicus.biologie.ens.fr/genomicus-plants
(Specific plants instance of Genomicus)
Service
https://www.genomicus.biologie.ens.fr/genomicus/
(Vertebrates instance of Genomicus)
Service
https://www.genomicus.biologie.ens.fr/genomicus-metazoa
(Specific metazoa instance of Genomicus)
Service
https://www.genomicus.biologie.ens.fr/genomicus-protists
(Specific protists instance of Genomicus)
Social media
https://twitter.com/GenomicusDB
(Genomicus Twitter)

Related Tools

GENOMICUS
Relation: uses