Genomicus-fungi
Genomicus-fungi provides synteny-based comparative genomics visualization and analysis to study the evolution of gene organization across fungal species.
Key Features:
- Multi-Dimensional Navigation: Provides linear chromosome-axis views, cross-species transverse comparisons, and chronological evolutionary time perspectives.
- Unlimited Genome Comparison: Supports comparison of an unlimited number of genomes within a broad phylogenetic context.
- Reconstructed Ancestral Gene Organization: Includes reconstructed ancestral gene organizations to interpret evolutionary events and genome-structure changes.
- Synteny-Based Visualization: Implements synteny analysis to visualize and compare genomic regions across species.
Scientific Applications:
- Evolution of Gene Organization: Investigating the evolution of gene organization within fungal species.
- Phylogenetic Relationships: Inferring phylogenetic relationships across fungi using conserved synteny patterns.
- Gene Conservation and Divergence: Identifying conserved genetic elements and divergence patterns across multiple species.
- Ancestral Genome Interpretation: Reconstructing and interpreting ancestral genome structures to study historical genome changes.
Methodology:
Performs synteny analysis to visualize and compare genomic regions and integrates reconstructed ancestral gene organizations for evolutionary interpretation.
Topics
Collections
Details
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- web application
- Added:
- 1/21/2020
- Last Updated:
- 6/16/2020
Operations
Data Inputs & Outputs
Dot plot plotting
Publications
Nguyen NTT, Vincens P, Roest Crollius H, Louis A. Genomicus 2018: karyotype evolutionary trees and on-the-fly synteny computing. Nucleic Acids Research. 2017;46(D1):D816-D822. doi:10.1093/nar/gkx1003. PMID:29087490. PMCID:PMC5753199.
Louis A, Nguyen NTT, Muffato M, Roest Crollius H. Genomicus update 2015: KaryoView and MatrixView provide a genome-wide perspective to multispecies comparative genomics. Nucleic Acids Research. 2014;43(D1):D682-D689. doi:10.1093/nar/gku1112. PMID:25378326. PMCID:PMC4383929.
Louis A, Muffato M, Roest Crollius H. Genomicus: five genome browsers for comparative genomics in eukaryota. Nucleic Acids Research. 2012;41(D1):D700-D705. doi:10.1093/nar/gks1156. PMID:23193262. PMCID:PMC3531091.
Muffato M, Louis A, Poisnel C, Crollius HR. Genomicus: a database and a browser to study gene synteny in modern and ancestral genomes. Bioinformatics. 2010;26(8):1119-1121. doi:10.1093/bioinformatics/btq079. PMID:20185404. PMCID:PMC2853686.
Downloads
- Biological dataftp://ftp.biologie.ens.fr/pub/dyogen/genomicus-fungi/Genomicus-fungi ftp download site providing reconstructed ancestral genomes with AGORA.