HastaLaVista

HastaLaVista provides statistical analysis and visualization for Nuclear Magnetic Resonance (NMR) untargeted metabolic profiling data to support discovery of metabolic perturbations.

Key Features:

• Integration of R and JavaScript: Combines R for statistical analyses with JavaScript for interactive visualizations.
• NMR-based untargeted spectral analysis: Supports processing and analysis of NMR untargeted metabolic profiling spectral datasets.
• Iterative analysis support: Enables iterative analysis workflows to investigate system perturbations.
• Enhanced data interoperability: Promotes interoperability for sharing and validation of metabolic profiling data.
• Extensible architecture: Architecture allows extension to interface with other scripting languages such as Python and to adapt to various types of data analyses.

Scientific Applications:

• Untargeted metabolic profiling: Facilitates untargeted spectral analysis to identify metabolic signatures and pathway perturbations from NMR data.
• Study of biological perturbations: Applied to investigate metabolic changes due to interventions or disease states, exemplified by analyses of bariatric surgery effects on rat metabolism.

Methodology:

Uses R for comprehensive statistical analyses and JavaScript for interactive visualizations.