HumanMine

HumanMine integrates heterogeneous genomic and biological data for Homo sapiens and Mus musculus to enable integrated queries and analyses supporting genomic, functional, and systems biology research.

Key Features:

• Data Integration: Leverages the InterMine extensible data model to integrate diverse biological data types across human and mouse.
• Customizable Query Facility: Provides a flexible query builder that supports complex, tailored queries across integrated datasets.
• Genomic Region Search: Supports targeted searches of specified genomic regions.
• Statistical Analysis Tools: Includes a library of 'widgets' that perform statistical analyses on query results.
• Data Export Options: Allows export of query results in numerous commonly used formats for downstream analysis.
• Extensibility: Permits extension of the data model and addition of new tools and functionalities.
• Web Services and Client Libraries: Exposes web services with client libraries in five commonly used programming languages.

Scientific Applications:

• Genomic research in human and mouse: Supports integrated analyses of datasets for Homo sapiens and Mus musculus.
• Comparative genomics: Facilitates cross-species comparisons between human and mouse genomic datasets.
• Functional genomics: Supports analysis of functional genomics datasets to investigate biological function.
• Systems biology: Enables integration of heterogeneous data types for systems-level analyses.

Methodology:

Built on the InterMine framework, HumanMine constructs integrated databases using an extensible data model and provides a fast, customizable query facility.