IA-Lab
IA-Lab provides MATLAB-based computational tools for high-throughput microscopy image analysis, enabling segmentation, measurement, and quantification of multidimensional and multichannel microscopy data.
Key Features:
- MATLAB implementation: Core functionality and workflows are implemented in MATLAB.
- Modular design: An object-oriented architecture enables customization and extension by replacing or adding components.
- Pre-defined analysis workflows: Includes workflows that parse multidimensional and multichannel images into analyzable formats.
- Segmentation: Provides tools for segmenting complex microscopy image data to isolate regions of interest.
- Measurement and quantification: Enables precise measurement and quantification of features within segmented images.
- Result export and visualization: Supports exporting results in multiple formats and displaying raw and processed images.
Scientific Applications:
- Intracellular transport quantification: Applied to quantify intracellular transport of internalized peptide-drug conjugates.
- Custom microscopy analyses: Supports development of tailored image-analysis solutions for unique microscopy experimental needs.
Methodology:
Object-oriented MATLAB architecture that enables integration of new analysis components with minimal code modification.
Topics
Details
- License:
- LGPL-3.0
- Tool Type:
- command-line tool
- Programming Languages:
- MATLAB
- Added:
- 11/14/2019
- Last Updated:
- 12/11/2020
Operations
Publications
Corrigan AM, Karlsson J, Wildenhain J, Knerr L, Ölwegård-Halvarsson M, Karlsson M, Lünse S, Wang Y. IA-Lab: A MATLAB framework for efficient microscopy image analysis development, applied to quantifying intracellular transport of internalized peptide-drug conjugate. PLOS ONE. 2019;14(8):e0220627. doi:10.1371/journal.pone.0220627. PMID:31369634. PMCID:PMC6675096.