IMMUNOPHARMACOLOGY

IMMUNOPHARMACOLOGY curates and documents molecular interactions between ligands and targets and integrates immunological data to support mechanistic and therapeutic research in immunopharmacology.

Key Features:

• Expert curation: IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY provides expert curation and comprehensive documentation of molecular ligand–target interactions.
• Immunological integration: Links pharmacological information to immune system interactions and immunological targets.
• Malaria pharmacology content: IUPHAR/MMV Guide to Malaria Pharmacology contains molecular targets within the malaria parasite, interaction data for ligands with antimalarial activity, and curated data from screening assays conducted against the whole organism.
• Resource integration: Connected with IUPHAR Guide to Pharmacology (www.guidetopharmacology.org), IUPHAR Guide to IMMUNOPHARMACOLOGY (www.guidetoimmunopharmacology.org), and IUPHAR/MMV Guide to Malaria Pharmacology (www.guidetomalariapharmacology.org).
• Partnerships: Collaborative content developed with the Medicines for Malaria Venture (MMV).

Scientific Applications:

• Immunopharmacology research: Support mechanistic studies of ligand–target interactions and immune-related mechanisms for scientists and clinicians.
• Antimalarial drug discovery: Provide molecular targets, ligand interaction data, and whole-organism screening assay results to identify and develop antimalarial therapies.
• Screening assay interpretation: Facilitate interpretation of screening assays used in antimalarial drug discovery, including whole-organism screens relevant to the WHO Africa Region.

Methodology:

Expert curation and integration of immunological data together with curation of molecular interaction data and screening assay results from whole-organism antimalarial assays.