LandScape

LandScape visualizes integrated genomic data as interactive landscape plots to compare gene- and pathway-level mutations and clinical attributes (e.g., age, gender, histology) across samples.

Key Features:

• Interactive Visualization: Dynamic, real-time visualization of summarized genetic information for exploratory analysis.
• Customizable Appearance: Built-in functions allow customization of visual elements for tailored presentation of genomic data.
• High-Quality Diagram Export: Supports export of publication-quality figures for inclusion in research outputs.
• Structured File Format and CSV Support: Accepts data in a structured file format and CSV files to represent diverse data types.
• Multi-panel Integration: Incorporates additional panels such as age, gender, and histology alongside genomic data.
• Comparative Mutation and Pathway Display: Enables comparison of genes and biological pathways mutated in cancers across datasets.
• Integration of Diverse Data Types: Combines multiple layers of genomic and sample-level data into a cohesive visualization.
• Real-time Exploration and Customization: Interactive controls permit on-the-fly exploration and adjustment of displayed data.

Scientific Applications:

• Comparative Cancer Genomics: Visual comparison of gene and pathway mutation patterns across cancer cohorts.
• Multi-layer Genomic Data Visualization: Illustration of integrated data from multiple layers or batch samples for cohort-level analyses.
• Personalized Medicine and Oncology Studies: Integration of clinical attributes (age, gender, histology) with genomic alterations to support translational investigations.

Methodology:

Integration of diverse data types via a structured file format (CSV supported) into an interactive visualization framework that enables real-time exploration and customization.