LongTR

LongTR accurately genotypes tandem repeats from high-fidelity long reads available from both PacBio and Oxford Nanopore Technologies.

Key Features:

• Long read compatibility: LongTR processes high-fidelity long reads from PacBio and Oxford Nanopore Technologies sequencing platforms.
• Genome-wide profiling: LongTR enables genome-wide profiling of genetic variation at tandem repeats.
• Accuracy for complex repeats: LongTR improves tandem repeat analysis especially for long or complex repeats.

Scientific Applications:

• Tandem repeat genotyping: LongTR genotypes tandem repeats across the human genome to analyze repeat length variation.
• Trait association studies: LongTR supports investigation of links between tandem repeat length variation and a variety of traits.

Methodology:

LongTR is a modified version of HipSTR.