MSIdV

MSIdV visualizes biological indices from mass spectrometry imaging (MSI) data to enable spatial mapping and interpretation of biochemical metrics such as the energy charge index on sample surfaces.

Key Features:

• Visualization of Biological Indices: Generates spatial maps of biological indices derived from MSI data, including indices such as the energy charge index.
• Signal Processing Capabilities: Incorporates signal processing routines to scan and process series of mass spectra for accurate index calculation.
• User-Defined Index Measures: Supports definition and visualization of custom index measures for tailored biochemical analyses.
• Implementation: Implemented in Python 2.7.

Scientific Applications:

• Proteomics: Enables spatial visualization of protein-related indices from MSI to support proteomic investigations.
• Metabolomics: Enables spatial visualization of metabolite-related indices from MSI to support metabolomic analyses.
• Pharmacology: Maps drug distribution and related indices on tissue surfaces to inform pharmacological studies.
• Disease mechanism and metabolic pathway studies: Supports investigation of molecular distributions and interactions on tissue surfaces to study disease mechanisms and metabolic pathways.

Methodology:

Signal processing routines scan and process series of mass spectra to calculate biological indices, with the software implemented in Python 2.7.