ModelTest-NG

ModelTest-NG selects best-fit nucleotide and amino acid substitution models for phylogenetic analyses to support accurate phylogenetic inference and comparative molecular evolution studies.

Key Features:

• Performance Efficiency: Achieves speeds one to two orders of magnitude faster than jModelTest and ProtTest while maintaining equivalent accuracy.
• Comprehensive Model Support: Supports a wide array of evolutionary models for nucleotide and amino acid substitutions, including ascertainment bias correction, mixture models, and free-rate models.
• Single-Partition Processing: Provides automatic processing of single partitions for model selection.

Scientific Applications:

• Phylogenetic Model Selection: Selecting best-fit substitution models to improve reconstruction of evolutionary relationships from molecular sequence data.
• Comparative Molecular Evolution: Enabling more reliable comparative studies by providing refined model choices for analyses of molecular evolution.

Methodology:

Reimplemented from scratch relative to jModelTest and ProtTest, improving computational efficiency and expanding the range of evolutionary models; includes ascertainment bias correction and mixture models.