NanoDefiner

NanoDefiner provides a decision-support framework to identify and categorize nanomaterials for regulatory compliance with the European Commission recommendation on the definition of nanomaterial (2011/696/EU).

Key Features:

• Tiered Approach: Employs a tiered methodology of screening and confirmatory stages to structure characterization and recommendation processes.
• Measurement Technique Recommendation: Recommends measurement techniques (MTs) tailored to specific materials based on the tiered assessment.
• Expert System Knowledge Base: Integrates an expert system knowledge base that encodes MT performance criteria and physicochemical properties of particle types to inform categorization decisions.
• Interoperability and Extensibility: Architected to be interoperable and extensible to accommodate forthcoming revisions of nanomaterial definitions and evolving scientific knowledge.
• Data Quality Assurance: Maintains data quality and validity through continuous revision processes.
• Validation through Case Studies: Has been validated by independent case studies focusing on industry-relevant particulate materials.

Scientific Applications:

• Regulatory Categorization: Supports identification and categorization of nanomaterials for registration and regulatory compliance with the European Commission recommendation on the definition of nanomaterial (2011/696/EU).
• Material Characterization Standardization: Provides a standardized approach to nanomaterial characterization by linking MT performance criteria with physicochemical properties.
• Research and Industry Support: Assists researchers and manufacturers in selecting measurement strategies and interpreting categorization outcomes for particulate materials.

Methodology:

Implements a tiered methodology with screening and confirmatory stages; recommends measurement techniques (MTs); uses an expert system knowledge base encoding MT performance criteria and physicochemical properties of particle types; applies continuous revision processes and validation via independent case studies on industry-relevant particulate materials.