OpenFlexure

OpenFlexure provides automated, customizable optical microscopy for scientific, educational, and clinical imaging, supporting trans-illumination, epi-illumination, polarisation contrast imaging, and epi-fluorescence modalities.

Key Features:

• Open-Source Design: Hardware and software are released open-source to enable community-driven customization and adaptation.
• 3D Printing Compatibility: Mechanical components are compatible with 3D printing for local fabrication.
• Automated Functionality: Includes motorized sample positioning and focus control for automated image acquisition.
• Imaging Modalities: Supports trans-illumination, epi-illumination, polarisation contrast imaging, and epi-fluorescence imaging.

Scientific Applications:

• Education: Provides microscopy capabilities for teaching and practical laboratory training in optical imaging techniques.
• Research: Enables versatile optical imaging experiments using transmitted, reflected, polarized, and fluorescence contrast methods.
• Clinical diagnostics: Supports detection of disease-relevant features using transmitted, polarized, and fluorescence imaging modalities.

Methodology:

Assembly and manufacture use 3D printing and integrate motorized sample positioning and focus control.