Pergola-web

Pergola-web converts longitudinal behavioral data into genomic-format representations and visualizes them using genome visualization technologies to enable computational analysis of high-throughput behavioral phenotyping.


Key Features:

  • Data processing (binning and grouping): Performs binning and grouping operations to organize and summarize longitudinal behavioral datasets.
  • Genomic-format conversion: Formats behavioral data into existing genomic formats to enable use of genomic analysis and visualization tools.
  • Genome-visualization rendering: Leverages genome visualization technologies to produce interactive visualizations of behavioral datasets across individuals and diverse data types.
  • Pergola Python library integration: Utilizes the Pergola Python library for data processing and format conversion workflows.
  • Scalability for high-throughput data: Scales to large longitudinal datasets generated by high-throughput behavioral phenotyping platforms.

Scientific Applications:

  • Longitudinal behavioral data analysis: Supports organization, summarization, and visualization of time-series behavioral measurements across individuals.
  • High-throughput phenotyping: Enables handling and interpretation of large datasets produced by high-throughput behavioral phenotyping platforms.
  • Application of genomics tools to behavioral science: Facilitates the application of bioinformatics and genome-visualization techniques to behavioral datasets.

Methodology:

Applies genomics standards to behavioral data processing; formats behavioral data into genomic formats; performs binning and grouping; and uses the Pergola Python library together with genome visualization technologies to render visualizations.

Topics

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
api, web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
Python
Added:
8/9/2019
Last Updated:
6/16/2020

Operations

Data Inputs & Outputs

Publications

Espinosa-Carrasco J, Pulido TH, Erb I, Dierssen M, Ponomarenko J, Notredame C. Pergola-web: a web server for the visualization and analysis of longitudinal behavioral data using repurposed genomics tools and standards. Nucleic Acids Research. 2019;47(W1):W600-W604. doi:10.1093/nar/gkz414. PMID:31106365. PMCID:PMC6602478.

PMID: 31106365
PMCID: PMC6602478
Funding: - Spanish Ministry of Economy, Industry and Competitiveness: BFU2014-55062-P, BFU2017-88264-P

Documentation

Links