RNAdt

RNAdt catalogs HTS-associated RNA structure probing methods and aggregates high-throughput sequencing (HTS) datasets to support transcriptome-scale RNA structuromics and analysis of RNA secondary and tertiary structure.

Key Features:

• Methodological compilation: Compiles an extensive collection of HTS-associated RNA structure probing methods relevant to RNA structuromics.
• Data accessibility: Aggregates HTS datasets derived from RNA structurome studies for downstream analysis.
• Comparative analysis support: Provides access to datasets that facilitate comparative analyses across studies and conditions.
• Method selection guidance: Documents methodological distinctions among probing approaches to assist selection of appropriate techniques for specific experimental goals.

Scientific Applications:

• Transcriptome-wide structure mapping: Enables analysis of RNA secondary and tertiary structures at transcriptomic scale using HTS-derived probing data.
• Functional RNA studies: Supports investigation of RNA roles in gene regulation, catalysis, ligand sensing, and environmental response by linking structure to function.

Methodology:

Compiles and catalogs HTS-associated RNA structure probing methods and aggregates corresponding HTS datasets from RNA structurome studies.