SLTChemDB
SLTChemDB consolidates detailed chemical composition data for smokeless tobacco (SLT) products to support chemical and toxicological research into SLT-associated toxicants and carcinogens.
Key Features:
- Extensive Chemical Data: Contains detailed information on 233 unique chemical compounds identified across 82 SLT brands, curated from literature and supplemented by data from chemical web servers and databases.
- Research Gap Identification: Highlights existing research gaps in chemical profiling of SLT compounds to inform further studies in chemistry and toxicology.
- Support for Tobacco Testing Laboratories: Provides foundational compound-level data that can be used by tobacco testing laboratories for further chemical and toxicological analysis.
- Policy Evidence Base: Supplies comprehensive, regularly updated chemical information to inform policy decisions aimed at controlling SLT use and mitigating health impacts.
Scientific Applications:
- Chemical and Toxicological Research: Enables analysis of chemical composition and toxicological properties of SLT compounds.
- Health Risk Identification: Facilitates identification of compounds potentially associated with toxicant exposure and carcinogenic risk.
- Exposure Assessment: Supports toxicologists in assessing exposure levels to specific SLT constituents.
- Mechanistic Studies: Aids investigation of mechanisms by which SLT chemicals may contribute to disease.
Methodology:
Data were extracted from existing literature and chemical databases, curated, and organized into a structured database format, with ongoing updates to incorporate new findings.
Topics
Details
- License:
- Unlicense
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- JavaScript, PHP
- Added:
- 8/9/2019
- Last Updated:
- 6/16/2020
Operations
Data Inputs & Outputs
Database search
Publications
Kaur J, Sharma A, Kumar A, Bhartiya D, Sinha DN, Kumari S, Gupta R, Mehrotra R, Singh H. SLTChemDB: A database of chemical compounds present in Smokeless tobacco products. Scientific Reports. 2019;9(1). doi:10.1038/s41598-019-43559-y. PMID:31073139. PMCID:PMC6509116.
PMID: 31073139
PMCID: PMC6509116
Funding: - Indian Council of Medical Research: Project No. BIC/14(01)/TF/2014
- World Health Organization: Reference No 2016/643768-0
Documentation
User manual
https://bic.icmr.org.in/sltchem/help.php