SLTChemDB

SLTChemDB consolidates detailed chemical composition data for smokeless tobacco (SLT) products to support chemical and toxicological research into SLT-associated toxicants and carcinogens.


Key Features:

  • Extensive Chemical Data: Contains detailed information on 233 unique chemical compounds identified across 82 SLT brands, curated from literature and supplemented by data from chemical web servers and databases.
  • Research Gap Identification: Highlights existing research gaps in chemical profiling of SLT compounds to inform further studies in chemistry and toxicology.
  • Support for Tobacco Testing Laboratories: Provides foundational compound-level data that can be used by tobacco testing laboratories for further chemical and toxicological analysis.
  • Policy Evidence Base: Supplies comprehensive, regularly updated chemical information to inform policy decisions aimed at controlling SLT use and mitigating health impacts.

Scientific Applications:

  • Chemical and Toxicological Research: Enables analysis of chemical composition and toxicological properties of SLT compounds.
  • Health Risk Identification: Facilitates identification of compounds potentially associated with toxicant exposure and carcinogenic risk.
  • Exposure Assessment: Supports toxicologists in assessing exposure levels to specific SLT constituents.
  • Mechanistic Studies: Aids investigation of mechanisms by which SLT chemicals may contribute to disease.

Methodology:

Data were extracted from existing literature and chemical databases, curated, and organized into a structured database format, with ongoing updates to incorporate new findings.

Topics

Details

License:
Unlicense
Maturity:
Mature
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
JavaScript, PHP
Added:
8/9/2019
Last Updated:
6/16/2020

Operations

Data Inputs & Outputs

Publications

Kaur J, Sharma A, Kumar A, Bhartiya D, Sinha DN, Kumari S, Gupta R, Mehrotra R, Singh H. SLTChemDB: A database of chemical compounds present in Smokeless tobacco products. Scientific Reports. 2019;9(1). doi:10.1038/s41598-019-43559-y. PMID:31073139. PMCID:PMC6509116.

PMID: 31073139
PMCID: PMC6509116
Funding: - Indian Council of Medical Research: Project No. BIC/14(01)/TF/2014 - World Health Organization: Reference No 2016/643768-0

Documentation