ST viewer

ST viewer integrates high-resolution imaging with spatially resolved transcriptome-wide sequencing to visualize and analyze Spatial Transcriptomics (ST) datasets and map gene expression within tissue sections.


Key Features:

  • Real-Time Interaction: Enables interactive exploration of Spatial Transcriptomics (ST) datasets with immediate feedback for dynamic data inspection.
  • Imaging–Sequencing Integration: Integrates high-resolution imaging with spatially resolved transcriptome-wide sequencing to associate spatial coordinates with transcriptomic profiles.
  • Comprehensive Visualization: Provides advanced visualization techniques to display spatial gene expression patterns across tissue sections.

Scientific Applications:

  • Tissue Architecture Analysis: Visualizes in situ gene expression to study the organization and function of cells within native tissue environments.
  • Disease Research: Identifies spatial gene expression patterns relevant to diseases such as cancer, including analysis of tumor microenvironments and metastatic processes.
  • Developmental Biology: Enables examination of gene expression during developmental stages to investigate cellular differentiation and organogenesis.

Methodology:

Combines high-resolution imaging with transcriptome-wide sequencing to map transcriptomic data onto tissue sections and provide a spatially resolved view of gene expression.

Topics

Details

License:
MIT
Maturity:
Mature
Cost:
Free of charge
Tool Type:
desktop application
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
7/6/2019
Last Updated:
11/24/2024

Operations

Publications

Fernández Navarro J, Lundeberg J, Ståhl PL. ST viewer: a tool for analysis and visualization of spatial transcriptomics datasets. Bioinformatics. 2018;35(6):1058-1060. doi:10.1093/bioinformatics/bty714. PMID:30875427.

PMID: 30875427
Funding: - INSTALZ–Neurodegenerative Disease Research: 643417

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