SyQADA

SyQADA orchestrates and automates bioinformatics workflows to manage task bookkeeping and enable reproducible processing of large-scale sequencing analyses.


Key Features:

  • Scalability and Versatility: Executes and repeats bioinformatics workflows across tens of thousands of samples and over 300,000 individual tasks on computing resources ranging from laptops to large clusters.
  • Computational Throughput: Demonstrates high computational capacity, evidenced by consumption of over 80 CPU-months in extensive analyses.
  • Workflow Bookkeeping and Reproducibility: Manages procedural bookkeeping and task orchestration to maintain transparent, repeatable, and reproducible workflow execution.

Scientific Applications:

  • Cancer Research (paired-sample analyses): Supports tumor–normal paired-sample studies by enabling reproducible execution of comparative sequencing workflows.
  • Diverse Bioinformatics Workflows: Applies to a wide array of bioinformatics analyses by providing a general workflow orchestration and bookkeeping framework.

Methodology:

Manages the intricate details of procedural bookkeeping to provide a transparent framework that ensures repeatable workflows and reproducible results.

Topics

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
workflow
Operating Systems:
Linux, Mac
Programming Languages:
Python
Added:
5/28/2019
Last Updated:
6/16/2020

Operations

Publications

Fowler J, San Lucas FA, Scheet P. System for Quality‐Assured Data Analysis: Flexible, reproducible scientific workflows. Genetic Epidemiology. 2018;43(2):227-237. doi:10.1002/gepi.22178. PMID:30565316. PMCID:PMC6571143.

PMID: 30565316
Funding: - National Human Genome Research Institute: R01HG005859 - Cancer Prevention and Research Institute of Texas: RP150079, RP160668 - National Cancer Institute: P30CA016672

Documentation