SyQADA
SyQADA orchestrates and automates bioinformatics workflows to manage task bookkeeping and enable reproducible processing of large-scale sequencing analyses.
Key Features:
- Scalability and Versatility: Executes and repeats bioinformatics workflows across tens of thousands of samples and over 300,000 individual tasks on computing resources ranging from laptops to large clusters.
- Computational Throughput: Demonstrates high computational capacity, evidenced by consumption of over 80 CPU-months in extensive analyses.
- Workflow Bookkeeping and Reproducibility: Manages procedural bookkeeping and task orchestration to maintain transparent, repeatable, and reproducible workflow execution.
Scientific Applications:
- Cancer Research (paired-sample analyses): Supports tumor–normal paired-sample studies by enabling reproducible execution of comparative sequencing workflows.
- Diverse Bioinformatics Workflows: Applies to a wide array of bioinformatics analyses by providing a general workflow orchestration and bookkeeping framework.
Methodology:
Manages the intricate details of procedural bookkeeping to provide a transparent framework that ensures repeatable workflows and reproducible results.
Topics
Details
- License:
- GPL-3.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- workflow
- Operating Systems:
- Linux, Mac
- Programming Languages:
- Python
- Added:
- 5/28/2019
- Last Updated:
- 6/16/2020
Operations
Publications
Fowler J, San Lucas FA, Scheet P. System for Quality‐Assured Data Analysis: Flexible, reproducible scientific workflows. Genetic Epidemiology. 2018;43(2):227-237. doi:10.1002/gepi.22178. PMID:30565316. PMCID:PMC6571143.
DOI: 10.1002/gepi.22178
PMID: 30565316
Funding: - National Human Genome Research Institute: R01HG005859
- Cancer Prevention and Research Institute of Texas: RP150079, RP160668
- National Cancer Institute: P30CA016672